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Tuberculosis in older adults: challenges and best practices in the Western Pacific Region

date_range 2023
person
Author Teo A.K.J.
description
Abstract The Western Pacific has one of the fastest-growing older adult populations globally, and tuberculosis (TB) remains one of the foremost infectious causes of disease and death in the region. Older adults are at higher risk of TB due to immunosenescence, comorbidities, and increased institutionalisation. Atypical symptoms and reduced access to health services may delay care-seeking and TB diagnosis, while co-morbidity and increased risk of adverse drug reactions complicate TB treatment. Post-TB sequelae and socioeconomic challenges may decrease the quality of life after TB treatment completion. Despite their high disease burden and special challenges, there is a lack of regionally coordinated policies and guidelines to manage TB among older adults. Routine TB screening at aged-care facilities, age-friendly infrastructure and services, awareness of atypical TB features, integration of TB and non-communicable diseases services, and person-centred approaches to treatment support could improve TB management among older adults. Addressing these challenges and adopting the best practices identified should inform policy formulation and implementation. Funding: This project was funded by 1) the World Health Organization Regional Office for the Western Pacific, with financial contributions from the Government of the Republic of Korea through the Korean Disease Control and Prevention Agency and the Government of Japan through the Ministry of Health, Labour and Welfare, and 2) NUS Start-up Grant. The funders had no role in the paper design, collection, analysis, and interpretation of data and in writing of the paper. © 2023
article
DOI 10.1016/j.lanwpc.2023.100770
language
Journal The Lancet Regional Health - Western Pacific
description
Source Scopus

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Citations Articles

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Risk factors for latent tuberculosis infection clustering among the elderly: a population-based cross-sectional study in Eastern China
Policy Impediments to Tuberculosis Elimination: Consequences of an Absent Medicare National Coverage Determination for Tuberculosis Prevention
The Western Pacific Regional Framework to End TB: overview and critical reflection
Integrating narrative and bibliometric approaches to examine factors and impacts of tuberculosis treatment non-compliance
Ending tuberculosis: challenges and opportunities
Immune aging and infectious diseases
Differences in clinical, radiological and laboratory parameters between elderly and young patients with newly diagnosed smear‐positive pulmonary tuberculosis in Vietnam
Representativeness and adverse event reporting in late-phase clinical trials for rifampin-susceptible tuberculosis: a systematic review.
Elderly age and tuberculosis: diagnostics difficulties and course features
The temporal trend of tuberculosis burden in an aging population in China: a secondary data analysis from the GBD 2019
Community-Wide Active Case Finding for Tuberculosis: Time to Use the Evidence We Have
Timing and predictors of death during treatment in patients with multidrug/rifampin-resistant tuberculosis in South Korea
Changing epidemic of tuberculosis amidst the COVID-19 pandemic in the Western Pacific Region: analysis of tuberculosis case notifications and treatment outcomes from 2015 to 2022
Effectiveness and safety of modified fully oral 9-month treatment regimens for rifampicin-resistant tuberculosis: a prospective cohort study
The Impact of Immune System Aging on Infectious Diseases
Is convenience really king? Comparative evaluation of catastrophic costs due to tuberculosis in the public and private healthcare sectors of Viet Nam: a longitudinal patient cost study
Community-based active-case finding for tuberculosis: navigating a complex minefield
Evaluation of Tuberculosis Treatment Results in Comparison of Indonesia and Neighboring Countries

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